Febin MThere are some magnificent and cool luxury Airbnb stays in Panama city with exquisite skyline views. Panama City is a vibrant destination that blends modern energy with rich history, making it highly appealing to tourists. Its striking skyline, filled with glittering skyscrapers along the Pacific coast, offers views often compared to Miami or Dubai. Visitors can enjoy rooftop cafés, seaside promenades, and sunset cruises that showcase the city’s dramatic high-rise silhouette. This modern backdrop sits beside colonial Casco Viejo and the famous Panama Canal, giving travelers a unique mix of urban glamour, culture, and tropical charm.
6 Outstanding luxury Airbnb stays in Panama City with skyline views
1. This magnificent luxury Airbnb in Panama City with skyline views
Listing name: Luxury 2BR w/Ocean Views – 27th Fl, Wanders YOO
Listing type: Entire rental unit
Max. no. of guests: 4
Attractions nearby: Albrook Mall, Metropolitan Natural Park, Parque Nacional Soberanía
This is an elegant luxury apartment Airbnb in Panama City that sleeps up to 4 guests in 2 bedrooms, complete with stylish designer furniture and sweeping city and ocean views. Guests can also enjoy full access to the building’s amenities like a pool, gym, and entertainment areas. Overall, it is ideal for couples or small groups wanting modern comfort in a central location.
Really impressive indeed.
2. luxury pet friendly Airbnb in Panama City with pool
Listing name: Ocean View Penthouse in YOO Panama 72nd Floor
Listing type: Entire rental unit
Max. no. of guests: 6
Attractions nearby: Poin Panamá, San Blas Islands, Panama Canal Museum
You can experience luxury high above Panama City in a spacious 3-bedroom pet friendly penthouse Airbnb that’s ideal for up to 6 guests. The bright, open living areas and spectacular balcony views are sure to create a memorable stay here. Additionally enjoy premium building amenities including pool, spa, gym, and dining options nearby for relaxation and fun.
Just Fantastic.
3. This stylish and premium retreat with gym facility
Listing name: Bristol Luxury apartment fully furnished – Model 2
Listing type: Entire apartment
Max. no. of guests: 2
Attractions nearby: Parque Omar, Avenida Balboa, Darien National Park
This is a fully furnished 1-bedroom apartment that’s perfect for couples or solo travelers. The indoors feature a comfortable living area, modern kitchen, and access to building facilities like a gym. Thus, it is a lovely luxury Airbnb in Panama City that offers a cosy staycation experience and convenient base for exploring the city.
A really cool retreat.
Also read: Best Airbnb Bocas del Toro Panama 2025: 8 Caribbean Island Getaways
4. This stunning premium apartment with pool
Listing name: Luxury apt in Panama City 2 Rooms 3 Baths
Listing type: Entire rental unit
Max. no. of guests: 4
Attractions nearby: Metropolitan Cathedral Basilica of Santa Maria the Ancient, El Nispero Zoo, National Theatre
This is a highly rated, guest-favorite apartment that offers 2 bedrooms and 3 bathrooms for up to 4 visitors. It is located in a stylish building with pool and leisure zones, and especially stands out for its spaciousness and comfort. Overall, it is Ideal for families or groups looking for upscale living in the heart of the city
A fabulous luxury Airbnb in Panama City.
5. This magnificent getaway with spa facility
Listing name: Unique Luxury 3-story Loft at the Yoo
Listing type: Entire rental unit
Max. no. of guests: 6
Attractions nearby: Museum of Panamanian History, City of Knowledge, Church Of The Society Of Jesus
This is a stylish, modern 3-bedroom loft in a Philippe Starck-designed building with city skyline and bay views. The open-plan space features sleek interiors, full kitchen, Wi-Fi and workspace. You can also enjoy premium building amenities like a pool, gym, and spa, all just steps from shopping, dining and waterfront attractions. Moreover, it is highly rated as well with self-check-in.
A brilliant luxury Airbnb.
Also read: Family-Friendly Airbnb Stays in Panama City Beach, Florida – Curated 2025
6. This fantastic oceanfront luxury Airbnb in Panama City
Listing name: Modern and luxurious oceanfront apartment
Listing type: Entire rental unit
Max. no. of guests: 4
Attractions nearby: Avenida Balboa, San Felipe, Bridge of the Americas
This is a stylish 2-bed, 2-bath apartment in a premium building with stunning ocean views, pool access, and self-check-in. It is centrally located as well near restaurants, shops, and amenities, and also offers a full kitchen, Wi-Fi, workspace, and free parking. The apartment is Ideal for up to 4 guests seeking comfort and great location with excellent reviews.
A brilliant oceanfront luxury Airbnb in Panama City.
For any more enquiries you can contact the Airbnb hosts.
